Clinical stages of Meibomian gland dysfunction MGD with therapeutic options
✅ Meibomian gland dysfunction Stage 1 criteria and management
✍️ no symptoms
✍️ Minimally altered secretions
✍️ no ocular surface staining
✍️ Inform patient about MGD
✍️ management
• Alter diet
• reduce environmental stress
• Consider lid hygiene
• warm compresses and expressions
✅ Meibomian gland dysfunction Stage 2 criteria and management
✍️ Minimal to mild symptoms of discomfort, itching, and photophobia
✍️ Minimal to mild altered secretions
✍️ none or limited ocular surface staining and TFBUT( tear film break up time ) <10s
✍️ management
• Improve ambient humidity
• increase dietary omega-3 intake
• Lid hygiene and warm expression (minimum of 4min twice daily)
• Lubricants
• topical azithromycin
• liposomal spray
• Consider tetracycline derivatives

✅ Meibomian gland dysfunction Stage 3 criteria and management
✍️ Moderate symptoms with defnite limitation of activity
✍️ Moderately altered secretions
✍️ increased lid margin vascularity
✍️ telangiectasia
✍️ orifice plugging
✍️ Mild to moderate conjunctival and peripheral corneal staining
✍️ TFBUT around 5s
✍️ management as stage 2 Plus
• oral tetracycline derivatives
• Lubricant ointment
• Consider anti-inflammatory therapy for dry eye
✅ Meibomian gland dysfunction Stage 4 criteria and management
✍️ Marked symptoms with definite limitation of activity
✍️ Severely altered secretions with MG dropout
✍️ displacement Central corneal staining
✍️ conjunctival inflammation and hyperaemia
✍️ TFBUT < 5s
✍️ management the same As stage 3 treatment Plus
• anti-inflammatory therapy for dry eye

✅ Meibomian gland dysfunction MGD Plus-disease
✍️ Exacerbated inflammatory ocular disease surface disease
✍️ Mucosal keratinization
✍️ Phlyctenular keratitis
✍️ trichiasis
✍️ MG cysts or chalazion
✍️ Anterior blepharitis
✍️ management by all previously mentioned options with
• Pulsed steroid therapy
• therapeutic CL/scleral CL
• Epilation
• cryotherapy
• Intralesional steroid or excision
• topical antibiotic or antibiotic-steroid combination
• tea tree oil scrubs
Meibomian gland dysfunction powerpoint presentation :
MGD…Unplugged
- MGD… Unplugged!New Developments, Treatment Considerations, Case Reviews Aaron Wolf, O.D.
- Sources• The International Workshop on Meibomian Gland Dysfunction – Investigative Ophthalmology & Visual Science, March 2011 – >50 international experts, M.D.’s, O.D.’s, Ph.D’s; >2 year period• The Tear Film and Ocular Surface Society• The Ocular Surface• Ophthalmology Management• Optometric Management• Review of Optometry• Contact Lens Spectrum• Personal observations and experiences in clinical practice
The A-Z of MGD
- The A to Zee of MGD reflections on the 2011 Workshop A J Bron Nuffield Department of Clinical NeuroSciences ,Oxford OXFORDSHIRE LOC Oct 23rd 2012
- Definition of MGD Meibomian gland dysfunction (MGD) is a chronic, diffuse abnormality of the meibomian glands, commonly characterized by terminal duct obstruction and/or qualitative/quantitative changes in the glandular secretion. This may result in alteration of the tear film, symptoms of eye irritation, clinically apparent inflammation, and ocular surface disease.

