Basal cell carcinoma ( BCC)
Squamous cell carcinoma (SCC)
Sebaceous gland carcinoma (SGC)
Malignant melanoma (MM)
Kaposi’s sarcoma (KS)
Merkel cell carcinoma (MCC)
Let’s see
Basal cell carcinoma
✍ Most common 90%
✍ Locally invasive ( rarely metastatic)
✍ Nodular type
☝ smooth rounded pearly edges
☝surface telangectasia
☝ central necrosis
✍ sclerotic type
☝ resembling chronic marginal blepharitis
✍ Common sites in sequence
☝ Lower Lid
☝Inner canthus
☝ Upper Lid
☝ Lateral canthus
✍ Risk factors
☝basal cell naveus syndrome
☝Xeroderma pigmentosa
☝old age
☝white skin
☝sun exposure
✍ treatment
☝wide local excision with safety margins 4mm by Mohs technique or frozen sections
Squamous cell carcinoma
✍ Less common 5%
✍ Highly malignant with metastatic
☝perineural spread
☝ lymphatic spread
✍ Nodular type
☝resembling BCC with leukoplakia
✍ sclerotic type
☝resembling chronic blepharitis
✍ Common site
☝Lower Lid
✍ Risk factors
☝xeroderma pigmentosa
☝old age
☝ white skin
☝ sun exposure
✍ Treatment
☝Wide local excision with Mohs technique or frozen sections
☝Exenteration( in orbital involvement)
☝Chemotherapy in metastasis
✅ Sebaceous glands carcinoma
✍ From meibomian gland or ziess gland
✍ Very rare 2%
✍ Highly fatal
☝10% without metastasis
☝67% with metastasis
✍ Common site
☝Upper Lid
✍ Risk factors
☝old age
☝ female
✍ Nodular type
☝resembling recurring chalazion
✍sclerotic type
☝resembling chronic blepharoconjunctivitis
✍ Pagetoid spread with skip lesions so mapping biopsy required
✍ Treatment
☝wide local excision with regional lymphadenectomy
☝ Exenteration ( if orbit involved)
Malignant melanoma
✍ Very rare 1%
✍ Highly fatal
☝50% if >1.5 mm thick in 5 yrs
✍ Risk factors
☝dysplastic naveus syndrome
☝xeroderma pigmentosa
☝ old white skin
☝ chronic sun exposure
✍ Local spread
☝horizontal
☝ vertical
✍ Metastatic
☝ hematologic
☝ lymphatic
✍ Treatment
☝ wide local excision with 10 mm safety margin
☝ Regional lymahadenectomy if 1.5 mm thick
☝ Chemotherapy if metastasis
Kaposi’s sarcoma
✍ Caused by HHV8
✍ Very rare
✍ Related to immunodeficiency
✍ Purple red nodular lesion
✍ Treatment
☝radiotherapy but not curative
Merkel cell carcinoma
✍ Highly malignant
✍ Extremely rare
✍ Rapidly growing purple nodular lesion
✍ Common site
☝ Upper Lid
