Ocular associations of Down Syndrome

Ocular associations of Down Syndrome

✍️✍️✍️Anterior segment in Ocular associations of Down Syndrome :

Lid (blepharitis, epicanthal fold, mongoloid slant)
• Nasolacrimal duct obstruction
• Cornea (keratoconus)
• Iris (brushfield spots, iris atrophy)
• Cataract.

Posterior segment in Ocular associations of Down Syndrome :

• Increased retinal vessels across optic disc
• Macular hypoplasia

Others from Ocular associations of Down Syndrome :

• High myopia
• Strabismus
• Nystagmus
• Amblyopia

Ocular associations of Down Syndrome powerpoint presentation :

Down syndrome Characteristics, Diagnosis, Prognosis, Treatment ( Ocular associations of Down Syndrome )

1. What is Down Syndrome ?  Down syndrome, named after John Langdon Down, the British physician who described the syndrome in 1866.  Down syndrome is the commonest autosomal chromosomal anomaly with an incidence of 1 in 800 to 1000 live births in all races and economic groups.  It is a chromosomal disorder caused by an error in cell division resulting in the presence of an additional third chromosome 21 or trisomy 21.
2. The problem occurs sometime shortly after fertilization; during the phase when cells are dividing rapidly.  One cell divides abnormally, creating a line of cells with an extra chromosome 21.  This form of genetic disorder is called a Mosaic.  Translocation-During cell division, the number 21 chromosome somehow breaks. A piece of the number 21 chromosome then becomes attached to another chromosome. Each cell still has 46 chromosomes, but the extra piece of chromosome 21 results in the signs and symptoms of Down syndrome. Translocations occur in about 3–4 percent of cases of Down syndrome.
3. Prognosis  Is variable depending on the types of complications of each      individual baby. The severity of the retardation can also vary significantly. Without the presence of heart defects, about 90 percent of children with Down syndrome live into their teens. People with Down syndrome appear to go through the normal physical changes of aging more rapidly, however. The average age at death for an individual with Down syndrome is about 50 to 55 years. Because of modern medical treatments, including antibiotics to treat infections and surgery to treat heart defects and duodenal atresia, life expectancy has greatly increased.
4. Men with Down syndrome appear to be uniformly sterile (unable to have offspring). • Women with Down syndrome, however, are fully capable of having babies. About 50 percent of these babies, however, will also be born with Down syndrome.
5. Most people have a six in 100 risk of developing Alzheimer’s, but people with Down syndrome have a one-in-four chance of the disease.  As people with Down syndrome age, they face an increased chance of developing the brain disease called Alzheimer’s (sometimes referred to Dementia or Senility).

Ocular associations of Down Syndrome videos :

Down syndrome (trisomy 21) – causes, symptoms, diagnosis ( Ocular associations of Down Syndrome ) – YouTube

https://www.youtube.com/watch?v=ze_6VWwLtOE

Ocular associations of Down Syndrome